A novel minisatellite repeat expansion identified at FRA16B in a Japanese carrier.
نویسندگان
چکیده
منابع مشابه
Human Chromosomal Fragile Site FRA16B Is an Amplified AT-Rich Minisatellite Repeat
Fragile sites are nonstaining gaps in chromosomes induced by specific tissue culture conditions. They vary both in population frequency and in the culture conditions required for induction. Folate-sensitive fragile sites are due to expansion of p(CCG)n trinucleotide repeats; however, the relationship between sequence composition and the chemistry of induction of fragile sites is unclear. To cla...
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1.Chamberlain, J.S., R.A. Gibbs, J.E. Ranier, P.N. Nguyen and C.T. Caskey. 1988. Detection screening of the Duchenne muscular dystrophy via multiplex DNA amplification. Nucleic Acids Res. 16:11141-11156. 2.Chou, Q., M. Russell, D.E. Birch, J. Raymond and W. Bloch. 1992. Prevention of prePCR mis-priming and primer dimerization improves low-copy-number amplifications. Nucleic Acids Res. 20:1717-1...
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Pancreatic AR42J cells have the feature of pluripotency of the precursor cells of the gut endoderm. Dexamethasone converts them to exocrine cells or liver cells. Using mRNA differential display techniques, we have identified a novel Ca2+-dependent member of the mitochondrial solute carrier superfamily, which is expressed during the course of differentiation, and have designated it MCSC. The cor...
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Human minisatellite B6.7 is a highly variable locus showing extensive heterozygosity with alleles ranging from six to >500 repeat units. Paternal and maternal mutation rates to new length alleles were estimated from pedigrees at 7.0 and 3.9% per gamete, respectively, indicating that B6.7 is one of the most unstable minisatellites isolated to date. Mutation at this locus was also analysed by sma...
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ژورنال
عنوان ژورنال: Genes & Genetic Systems
سال: 2000
ISSN: 1341-7568,1880-5779
DOI: 10.1266/ggs.75.149